ObjectiveTo create a visualization method for predicting the target position of orthodontic treatment.MethodsThe adult patients whose facial appearance needs to be improved greatly, diagnosed as Class Ⅰ or Class Ⅱ and whose CO-CR position was basically the same were recruited and treated with tooth extraction.The basic information of the patients were recorded, the lateral radiographs and face photos as well as plaster models before and after treatment collected, the model established using three-dimensional model scanner, and then the teeth arranged by 3 Shape Ortho Analyzer software.Dolphin imaging 11.95 Premium software was used to form profile prediction and generate lateral images.ResultsThe final results of hard and soft tissues were similar to the actual results, which can effectively predict VTO for orthodontic patients.ConclusionWhen combining the three-dimensional model based on the two-dimensional design for teetch arrangement, the tooth position prediction is more accurate, which can help orthodontists set the treatment target position and faciliate the dentists’ design of tooth extraction and anchorage position.