18F-FDG PET/CT在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值
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福建医科大学 教学医院,福建省肿瘤医院 核医学科,福州350014

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R733.4

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18FFDG PET/CT in Diagnosis of Primary Cervical Cancer and Pelvic Lymph Node Metastasis
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Department of Nuclear Medicine, Fujian Provincial Tumor Hospital,Teaching Hospital of Fujian Medical University, Fuzhou 350014, China

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    摘要:

    目的评估18F氟脱氧葡萄糖正电子发射断层显像(18FFDG PET/CT)在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值。方法回顾性分析57例宫颈癌患者病历资料,将治疗前18FFDG PET/CT检查结果与术后病理结果进行比较。结果宫颈癌原发灶18FFDG PET/CT检查阳性55例,阴性2例,诊断敏感度96.5%(55/57)。22例经手术治疗患者中,9例(9/22,40.9%)经手术病理证实盆腔淋巴结转移。18FFDG PET/CT诊断宫颈癌盆腔淋巴结转移的敏感度、特异度、准确度、阳性预测值和阴性预测值分别为66.7%(6/9)、92.3%(12/13)、81.8%(18/22)、85.7%(6/7)、80.0%(12/15)。结论18FFDG PET/CT诊断宫颈癌原发灶具有极高的敏感度,能有效地检出宫颈癌原发灶;诊断宫颈癌盆腔淋巴结转移特异度较高,但敏感度一般,特别是短径<1.0 cm淋巴结。

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    ObjectiveTo evaluate the clinical value of 18Ffluorodeoxyglucose positron emission tomography(18FFDG PET/CT) in the diagnosis of primary cervical cancer and pelvic lymph node metastasis.MethodsThe clinical data of 57 patients with cervical cancer were retrospectively analyzed.All patients underwent 18FFDG PET/CT scanning pretherapy.The diagnostic results of 18FFDG PET/CT were compared with postoperative pathological findings.ResultsOf the 57 patients with pathologically confirmed cervical cancer,18FFDG PET/CT was positive in 55(55/57,96.5%)patients and negative in 2(2/57,3.5%)patients in the primary lesion.The sensitivity of 18FFDG PET/CT was 96.5%(55/57).In with 22 patients who underwent surgical treatment, 9(9/22,40.9%) were confirmed pelvic lymph node metastasis by postoperative pathological findings.The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 18FFDG PET/CT in detect the pelvic lymph node metastasis were 66.7%(6/9),92.3%(12/13),81.8%(18/22),85.7%(6/7),80.0%(12/15),respectively.Conclusions18FFDG PET/CT has a high sensitivity in diagnosis of the primary lesion of cervical cancer, it can effectively detect primary tumors; in pelvic lymph node metastasis, the diagnosis specificity of this method is high, but sensitivity is moderate, especially the short diameter <1.0 cm lymph nodes.

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张杰平, 唐明灯, 林端瑜, 蔡志华.18F-FDG PET/CT在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值[J].福建医科大学学报自然版,2013,(6):382-385

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