Objective To investigate the molecular epidemiology of carbapenem-resistant Acinetobacter baumannii(CRAB)strains collected from intensive care units(ICUs)in our hospital. Methods 34 CRAB strains were collected and isolated at ICUs of our hospital during the period of September 2010 to April 2012, of which 25 from general ICU, and 9 from Burn ICU. Genotyping was performed by Diversilab repetitive element PCR system. Results There were 4 types of CRAB strains, including type A, B, C and D. Type A and D CRAB strains existed in Burn ICU Type A dominated. Type B, C and D CRAB strains were found in general ICU with Type D dominant. Conclusion The epidemic strains of CRAB in Burn ICU was different from that in general ICU, and the type D CRAB strain appeared simultaneously in both the ICUs suggesting that a cross infection may prevail in the two ICUs.