ObjectiveTo investigate the clinical features and the treatment of primary splenic lymphoma.MethodsThe clinical data and followup surveys of 26 cases with primary splenic lymphoma, treated from January 2003 to June 2013, were analyzed retrospectively.ResultsLeft upper abdominal pain(68.38%), fever(46.15% ), anemia(46.15%), and spleonmegaly(100%) were the main clinical symptoms.Histopathology showed that nonHodgkin lymphoma accounted for 25 of the cases (96.15%) and 1 case was of Hodgkin’s Lymphoma.Based on the Ahmann clinical staging of splenic lymphoma, the stageⅠ disease accounted for 6 of the patients (23.08%), stage Ⅱ accounted for 5 (19.23%), and stage Ⅲ accounted for 15 (57.69%).The 1year and 5year overall survival rates were 60% and 30%.ConclusionsPrimary splenic lymphoma is a rare lymphoma, surgery to remove even multivisceral resection can improve the survival rate, and conducive to the further diagnosis.