泉州市沿海地区亚临床甲状腺功能减退症的调查分析
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福建医科大学 附属第二医院,泉州3620001. 内分泌代谢科;
2. 妇产科

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R347.2; R581

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The Survey of Subclinical Hypothyroidism in Quanzhou Coastal Area
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1. Department of Endocrinology and Metabloism, The Second Affiliated Hospital of Fujian Medical University, Quanzhou362000, China;
2. Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China

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    摘要:

    目的研究泉州市沿海地区人群亚临床甲状腺功能减退症(SCH)的流行特征,并探讨SCH患者血清促甲状腺素(TSH)与血压的关系。方法采用整群随机抽样方法调查泉州市21个沿海社区的常住(居住时间≥5年)居民1 742人,年龄≥30岁,检测血压、游离三碘甲状腺原氨酸、游离甲状腺素和TSH、空腹血糖、甘油三酯。采用t检验、多元线性相关分析进行数据统计。结果(1)SCH总患病率3.90%,其中女性4.24%,男性2.99%,男女间差别无统计学意义(P>0.05)。(2)从年龄结构看,30~39岁组患病率最高(4.74%),其中女性为5.24%;60~69岁组患病率最低(2.58%)。(3)TSH与舒张压水平呈正相关(β=0.064,P<0.05)。结论泉州市沿海地区年轻女性SCH患病率较高;SCH可能是血压升高的危险因素。

    Abstract:

    ObjectiveTo investigate the prevalence of subclinical hypothyroidism(SCH) and discuss the relationship between thyroid stimulating hormone (TSH) and blood pressure in population of Quanzhou city.MethodsA total of 1 742 persons over thirty years old who had lived in this area at least five years were randomly enrolled.The data of blood pressure, thyroid function, fasting plasma glucose(FPG), triglyceride(TG) were collected.All data were analyzed by SPSS 18.0 software.ResultsThe overall SCH prevalence was (3.90%), and there was not significant difference between females (4.24%)and males (2.99%)(P>0.05).The SCH prevalence in the people of thirty to thirty-nine age group(4.74%) was higher than that in the people of sixty to sixty-nine age group(2.58%), and the females of thirty to thirty-nine age group had highest SCH prevalence.Furthermore, there was a positive correlation between TSH level and diastolic blood pressure(DBP) (β=0.064, P<0.05).ConclusionThe prevalence of SCH is higher in young females in Quanzhou coastal area and SCH may be a risk factor in high blood pressure.

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周竟雄, 李鲁宏, 张子平, 黄惠斌, 陈晓毓, 李希圣.泉州市沿海地区亚临床甲状腺功能减退症的调查分析[J].福建医科大学学报自然版,2015,(2):101-104

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