儿童颅咽管瘤显微手术治疗的临床分析
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福建医科大学 附属第一医院神经外科,福州350005

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R725.8; R726.192

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收稿日期: 2015-05-25
基金项目: 福建省临床重点专科项目
作者单位: 福建医科大学 附属第一医院神经外科,福州350005
作者简介: 张元隆(1984-),男,住院医师,福建医科大学2008级硕士研究生
通讯作者: 吴喜跃.Email:1371860869@qq.com


The Clinical Analysis of Microsurgery Therapy in Pediatric Craniopharyngioma
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Department of Neurosurgery ,The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005,China

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    摘要:

    目的探讨儿童颅咽管瘤影像学特征、显微手术方法及术后并发症的防治。方法回顾性分析19例颅咽管瘤儿童的临床资料(包括影像学特征、手术入路、术后并发症等)。结果19例患儿全切除14例(73.7%),次全切除5例(26.3%)。手术入路包括经额底纵裂入路10例,经翼点入路7例,经胼胝体-穹隆间入路2例;术后并发症:尿崩症15例,电解质紊乱14例,垂体功能低下10例,癫痫5例,颅内感染4例,中枢性高热3例。围手术期无死亡病例。随访19例,垂体功能低下需要长期激素替代10例,因垂体功能低下死亡2例。结论术前的影像学评估、合理的手术入路、术后并发症的积极防治是改善颅咽管瘤预后的重要环节。

    Abstract:

    ObjectiveTo explore the image characteristics, microsurgery methods and the prevention and treatment of postoperative complications of craniopharyngioma in children.MethodsClinical information of 19 cases of pediatric craniopharyngioma receiving surgical procedure, including image characteristics, surgical approaches and postoperative complications, were analyzed retrospectively.ResultsTotal resection was performed in 14 cases(73.7%), subtotal resection in 5 cases(26.3%).Three different approaches were used, including the fronto-basal interhemispheric approach(10 cases), the pterion approach(7 cases), and the transcallosal-interforniceal approach(2 cases).The postoperative complications were as follows: diabetes insipidus in 15 cases, electrolyte disorder in 14 cases, hypopituitarism in 10 cases, epilepsy in 5 cases, intracranial infection in 4 cases, and central high fever in 3 cases.There was no case of death in peroperative period.19 cases were followed up.10 cases of hypopituitarism needed long-term hormone replacement, 2 cases died because of hypopituitarism.ConclusionPreoperative image evaluation, proper choice of surgical approach and active prevention and therapy of postoperative complication are important links in improving the prognosis of craniopharyngioma.

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张元隆, 梅文忠, 陈剑舞, 吴喜跃, 康德智.儿童颅咽管瘤显微手术治疗的临床分析[J].福建医科大学学报自然版,2015,(4):249-251

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