ObjectiveTo explore prognostic factors in patients of radiotherapy with mid-stage and advanced-stage uterine cervix carcinoma and to provide reference for clinical diagnosis, treatment, and prognosis evaluation of cervix carcinoma.MethodData of 603 cases with mid-stage and advanced-stage uterine cervix carcinoma were retrospectively analyzed, and statistical methods were used to analyze clinical features and prognostic features of the case.Kaplan-Meier method and Log-rank were adopted for survival single factor analysis, and Cox stepwise regression model was used for multiple-factor analysis.ResultThe follow-up time (median) was 31 months, and the 1, 2 and 3-year survival rates were 91.5%, 88.4% and 86.9% respectively.As indicated by Kaplan-Meier survival analysis, tumor differentiation upon diagnosis, FIGO staging, lymphatic metastasis, concurrent cardiovascular disease and other complications, pre-treatment anemia, concurrent radiochemotherapy during a therapeutic course, application of intensity modulated radiotherapy, and supportive thermal therapy were related with patients’ prognosis.It is indicated by multi-factor analysis that concurrent lymphatic metastasis upon diagnosis and supportive thermal therapy during a therapeutic course were independent factors for prognosis of patients with mid-stage and advanced-stage uterine cervix carcinoma.ConclusionIn patients with mid-stage and advanced-stage uterine cervix carcinoma, concurrent lymphatic metastasis upon diagnosis, and supportive thermal therapy during a therapeutic course are independent factors for the prognosis.Detailed evaluation of a patient’s condition upon diagnosis facilitates better prediction of her prognosis, and supportive thermal therapy during a therapeutic course and other comprehensive therapeutic approaches effectively improve long-term survival rate of the patients.